Airways with mucus plugs have thicker epithelium, basement membranes and smooth muscle than unplugged airways. These thicker features occur in patients with fatal and nonfatal asthma alike. WASHINGTON ...

Today, there is a broader understanding of asthma, including the genetic, environmental, and host-related factors that contribute to declining lung function in patients. Asthma affects up to 13% of ...

Changes that occur in the airways of asthma patients are in part caused by the naturally occurring protein interleukin-13 (IL-13) which stimulates invasion of airway cells called fibroblasts, ...

Researchers suggest protein that acts in combination with other agents to cause changes that lead to loss of lung function. An invasion of fibroblasts stimulated by the naturally occurring protein ...

When asthma is severe and long term, it becomes less amenable to treatment -- or less "reversible." This process, remodeling of the airways with peribronchial fibrosis, has been widely attributed to ...

NASHVILLE, Tenn. — There are no simple solutions in asthma treatment, as evidenced by a debate that covered airway remodeling and the use of oscillometry among other topics at the CHEST Annual Meeting ...

Thirty asthmatic patients and thirty control subjects were enrolled. Asthmatic subjects used inhaled Symbicort 4.5/160 μg twice daily for one year. The effect of formoterol-budesonide on airway ...

New research from the La Jolla Institute for Immunology has brought a novel, long-term treatment for severe asthma a step closer. Building on a decade of work, the new findings present a potential way ...

A recent case report described 3 pediatric patients with severe asthma whose disease was not managed according to care guidelines and who did not respond to the biologic by the time they began therapy ...

(Ivanhoe Newswire) -- Asthma is a common chronic respiratory condition characterized clinically by an excessive tendency toward reversible airway narrowing. Scientists believe that the airway ...

'This is a very striking and significant result that essentially separates LIGHT from any of the other inflammatory cytokines that have been implicated in the process in severe asthmatics.' An ...