Epigenome remodeling, including widespread changes to DNA methylation and 3D chromatin structure, is increasingly recognized as an important mechanism of gene deregulation in cancer. For example, at ...

The field of cancer epigenetics examines how heritable changes in gene regulation - independent of DNA sequence - impact ...

Epigenetic age acceleration appears to be associated with worse neurocognitive function for those that survive childhood ...

Patients with recurrent metastatic non-small cell lung cancer have a morbid prognosis, but a new epigenetic therapy may have potential in this population, according to data published in Cancer ...

Winston-Salem, NC and Charlottesville, VA - Much of the variability in severity, organ involvement, and response to therapy among patients with systemic lupus erythematosus (SLE) is blamed on ...

Diffuse midline glioma (DMG), H3K27-altered, is a lethal pediatric high-grade tumor, lacking effective treatment options, primarily depending on clinical trials. Epigenetic agent-based immunotherapy ...

Armed with $68 million in Series B funding, Epicrispr Biotechnologies (Epic) is initiating human trials of its lead candidate EPI-321, an epigenetic therapy for the neuromuscular disorder, ...

The accuracy of cell-free DNA blood-based tests in the detection of gastric cancer: An exploratory meta-analysis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract ...

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new ...