Faulty lipid regulation in CLL patients impairs T-cell function, affecting treatment outcomes and resistance to current therapies. Differences in lipid metabolism between CLL patients and healthy ...
Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid ...
FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARĪ³, peroxisome proliferator-activated receptor ...
Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC). This ...
A research team has developed a fluorescent probe that allows scientists to visualize how individual lipid droplets break down inside living cells in real time. The probe changes its fluorescence ...
Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...
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