“It’s genuinely surprising that the add-on gives vancomycin any ability at all to hit gram negatives,” says Kim Lewis, an antibiotic researcher at Northeastern University who was not involved in the ...

A team of Princeton researchers led by Prof. Zemer Gitai have found an antibiotic that can simultaneously puncture bacterial walls and destroy folate within their cells -- taking out even monstrous ...

Cefiderocol is effective against various gram-negative bacterial infections, with combination therapy offering no clinical advantage over monotherapy.

• Require X (hemin) and/or V (nicotinamide adenine dinucleotide) factors for growth • Responsible for 0.5–1% of all cases of IE • Haemophilus aphrophilus is the most common species responsible for IE ...

Clinical Infectious Diseases, Vol. 25, Supplement 2. Proceedings of the 1996 Meeting of the Anaerobe Society of the Americas (Sep., 1997), pp. S107-S110 (4 pages) During our studies of the bacterial ...

Gram-negative bacteria's thick outer membrane prevents entry of toxic molecules, including antibiotics. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to ...

Gram-negative bacteria, notorious for their intrinsic and acquired resistance mechanisms, pose a significant threat to public health. The emergence of ...

The spread of multidrug-resistant (MDR) bacteria is a serious public health threat, and new drug options for Gram-negative bacteria are in particularly urgent need. A group of researchers at Genentech ...