The Prostate Cancer Prevention Trial (PCPT) of finasteride for prostate cancer prevention resulted in a 24.8% reduction in the 7-year period prevalence of prostate cancer for patients taking ...

Key challenges of biopsy-based determination of prostate cancer aggressiveness include tumour heterogeneity, biopsy-sampling error, and variations in biopsy interpretation. The resulting uncertainty ...

While the majority of prostate cancers are detected in the peripheral zone (PZ), [1] recent MRI data suggest that the anterior zone (AZ) of the prostate, an area that is not palpable on digital rectal ...

MRI technology has been melded with a traditional ultrasound prostate exam to create a three-dimensional map of the prostate that allows physicians to view growths that were previously undetectable.

In a study of patients undergoing transperineal prostate biopsy, the detection rate of clinically significant prostate cancer did not differ significantly between targeted biopsy (TB) with fewer ...

This trial establishes that lesion-targeted and systematic sampling are both required to maximize the accuracy of prostate biopsy. In the past decade, MRI-guided biopsy methods, which are more ...

Compared with systematic biopsy, MRI-directed targeted biopsy reduces the risk of overdiagnosis of prostate cancer for men with elevated prostate-specific antigen levels, according to researchers.

Current prostate cancer screenings leave a lot to be desired, with its notorious inaccuracies giving men and their doctors a lot to worry about. Scientists are on it. The many newer tests currently ...

Compared with peripheral zone prostate cancers, transitional zone cancers are less prevalent and tend to have more favorable pathological characteristics. It may be possible to spare sampling of the ...

Each year, 1 million men in the U.S. undergo biopsies to determine whether they have prostate cancer. The biopsy procedure traditionally has been guided by ultrasound imaging, but this method cannot ...

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Background: The prostatic anterior zone (AZ) is not targeted routinely by TRUS guided prostate biopsy (TRUS-Pbx). MRI is an accurate diagnostic tool for AZ tumors, but is often unavailable due to cost ...