Ning et al. set out to study the interactive network between BMP and TGF-β pathways in HCCs. They utilized the gene-expression profiles of 359 HCC samples provided by The Cancer Genome Atlas, in ...
The epithelial-to-mesenchymal transition (EMT) plays a critical role during normal development and in cancer progression. EMT is induced by various signaling pathways, including TGF-β, ...
Schematic representation of different strategies targeting TGF-β signaling for liver fibrosis therapy. TGF-β signaling inhibitors hold important therapeutic potential for hepatic fibrosis. Although ...
This is a preview. Log in through your library . Abstract Nuclear translocation of Smad proteins is a critical step in signal transduction of transforming growth factor β (TGF-β) and bone ...
Mouse Avatar Models of Colorectal Cancer Liver Metastasis: The Molecularly Annotated Platforms for Preclinical Evaluation of Novel Therapeutics Background: Oral squamous cell carcinoma (OSCC) is a ...
CYR61, cysteine-rich angiogenic inducer 61; FT, factors of transcription; LATS, large tumor suppressor; MOB, mob kinase activator; MST, mammalian sterile 20-like ...
Screening of differentially expressed genes of esophageal squamous cell carcinoma with cDNA microarray. This is an ASCO Meeting Abstract from the 2019 ASCO Annual Meeting I. This abstract does not ...
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