Northwestern University scientists have uncovered a hidden molecular "control switch" inside a protein that helps the body ...

Fungal infections kill millions of people each year, and modern medicine is struggling to keep up. But researchers at ...

The brain’s chatter has always been partly out of reach, with electrical spikes easy to record but the chemical whispers ...

PEGASUS generates permeable macrocyclic peptides, offering new promise for a modality that can combine the properties of a biologic in a pill ...

Whether you’re interested in why a living system works as it does or the reasons it goes awry, proteins are a critical part of the molecular picture. The proteins circulating in a person’s plasma can ...

New work could help produce more effective future anti-aging treatments. The way the body ages could be more resilient than previously thought, a new study suggests. Published in the Journal of the ...

In the pharmaceutical discovery process, understanding a drug’s residence time—the duration a molecule remains bound to its ...

If cells are the factories, proteins are the workers. They control nearly every aspect of cell function, from structure to signaling, from transport to defense. And, like many workers, they rarely act ...

The artistic rendering depicts proteins (colored shapes) being analyzed by solid-state nanopores under varying voltage conditions. By combining nanopore signals with machine learning, researchers can ...

Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...