Navigating the complexities of cyclohexane conformations can be challenging, especially when determining the most stable ring flip for substituted cyclohexanes. Understanding these conformational ...

The cyclohexane framework, adopting a chair conformation, is a cornerstone concept in organic chemistry, influencing the properties and reactivity of countless molecules. This specific conformation ...

Researchers in China have synthesised a series of molecules that resemble supersized versions of cyclobutane, cyclopentane and cyclohexane. Cycloalkanes adopt puckered conformations to help relieve ...

Confirmation bias is a psychological term for the human tendency to only seek out information that supports one position or idea. This causes you to have a bias towards your original position because ...

Pete Hegseth was narrowly confirmed as defense secretary amid swirling questions about his competence and character, and despite GOP Senators Murkowski and Collins standing up and opposing him. Others ...

The way proteins move is often what gives them biological activity: they can open, close, twist, and rearrange themselves in ways that allow them to bind to other molecules or perform complex ...

CANTON, Mass.--(BUSINESS WIRE)-- Conformation-X Therapeutics, LLC, an immune-oncology focused drug development company, announced today that it has closed an oversubscribed funding tranche of $3.65M, ...

This fundamental study provides compelling evidence to explain how chemical variations within a set of kinase inhibitors drive the selection of specific Erk2 conformations. Conformational selection ...

Histone post-translational modifications (PTMs) play a critical role in chromatin regulation. It has been proposed that these PTMs form localized ‘codes’ that are read by specialized regions (reader ...