Researchers in China have synthesised a series of molecules that resemble supersized versions of cyclobutane, cyclopentane and cyclohexane. Cycloalkanes adopt puckered conformations to help relieve ...
Confirmation bias is a psychological term for the human tendency to only seek out information that supports one position or idea. This causes you to have a bias towards your original position because ...
The way proteins move is often what gives them biological activity: they can open, close, twist, and rearrange themselves in ways that allow them to bind to other molecules or perform complex ...
CANTON, Mass.--(BUSINESS WIRE)-- Conformation-X Therapeutics, LLC, an immune-oncology focused drug development company, announced today that it has closed an oversubscribed funding tranche of $3.65M, ...
This fundamental study provides compelling evidence to explain how chemical variations within a set of kinase inhibitors drive the selection of specific Erk2 conformations. Conformational selection ...
In this excerpt from Shoeing the Modern Horse by Steven Kraus, CJF, with Katie Navarra, the head of farrier services at Cornell University explains the importance of understanding conformational ...
the atoms in a molecule and is an important task in bioinformatics and pharmacology. Previous methods usually first predict the interatomic distances, the gradients of interatomic distances or the ...
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